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One drop of Xiidra is used twice daily in each eye1
  • Xiidra is used once in the morning and once in the evening, approximately 12 hours apart1

  • Discard the single-use container immediately after use1

  • Xiidra comes in a 30-day supply1

  • Xiidra is a preservative-free, sterile solution with a neutral pH range of 7.0 to 8.01

  • Contact lenses should be removed before using Xiidra and may be put back in 15 minutes after using the treatment1

  • Systemic exposure following topical ophthalmic administration to Xiidra was low in studies1

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Xiidra® (lifitegrast ophthalmic solution) 5% is indicated for the treatment of signs and symptoms of dry eye disease (DED).

Important Safety Information

Xiidra is contraindicated in patients with known hypersensitivity to lifitegrast or to any of the other ingredients.

In clinical trials, the most common adverse reactions reported in 5-25% of patients were instillation site irritation, dysgeusia and reduced visual acuity. Other adverse reactions reported in 1% to 5% of the patients were blurred vision, conjunctival hyperemia, eye irritation, headache, increased lacrimation, eye discharge, eye discomfort, eye pruritus and sinusitis.

To avoid the potential for eye injury or contamination of the solution, patients should not touch the tip of the single-use container to their eye or to any surface.

Contact lenses should be removed prior to the administration of Xiidra and may be reinserted 15 minutes following administration.

Safety and efficacy in pediatric patients below the age of 17 years have not been established.

Please click here for Full Prescribing Information.


  1. Xiidra [Prescribing Information]. Lexington, MA: Shire US.